Impact of an Antimicrobial Stewardship and Emergency Department Initiated Dalbavancin Guideline for Patients with Acute Bacterial Skin and Soft-Tissue Infections

Emergency Department Specific Antimicrobial Stewardship Intervention Reduces Antibiotic Duration and Selection for Discharged Adult and Pediatric Patients with Skin and Soft-tissue infections

Antimicrobial Stewardship in the Emergency Department

The literature contains robust evidence on the positive impact of antimicrobial stewardship programs (ASP) in the inpatient setting. With national policies shifting toward provisions of quality health care, the impetus to expand ASP services becomes an important strategy for institutions. However data on stewardship initiatives in other settings are less characterized. For organizations with an...

267Dalbavancin for the treatment of Streptococcal Skin Infections

Background. Streptococci are a known cause of complicated skin and soft tissue infections (cSSTI). Dalbavancin, a lipoglycopeptide antibiotic has been studied in 3 global phase 3 randomized, double-blind, controlled trials for the treatment of acute bacterial skin and skin structure infections (ABSSSI) and cSSTI. The objective of this analysis is to evaluate outcomes for patients with streptoco...

Once-weekly dalbavancin versus standard-of-care antimicrobial regimens for treatment of skin and soft-tissue infections.

Dalbavancin, a novel glycopeptide with a long elimination half-life ( approximately 9-12 days), was compared to standard antimicrobial therapy for skin and soft-tissue infections (SSTIs). In a randomized, controlled, open-label, phase 2 proof-of-concept trial, adults received 1100 mg of dalbavancin (as a single intravenous infusion), 1000 mg of dalbavancin intravenously and then 500 mg intraven...

Assessments of Opportunities to Improve Antibiotic Prescribing in an Emergency Department: A Period Prevalence Survey

INTRODUCTION Approximately 30% of all outpatient antimicrobials are inappropriately prescribed. Currently, antimicrobial prescribing patterns in emergency departments (ED) are not well described. Determining inappropriate antimicrobial prescribing patterns and opportunities for interventions by antimicrobial stewardship programs (ASP) are needed. METHODS A retrospective chart review was perfo...